New Australian 3-monthly birth control injection

April 13, 2008 – 6:53 am

According to news.com.au, a new Australian-developed contraceptive jab for men, taken four times a year, has been proven to be just as effective as birth-control pills for women.

The new jab works by suppressing sperm output but does not have a permanent effect. It’s a combination of androgen and progestin - mostly testosterone - it needs to be administered every two to three months. Researchers from the ANZAC Research Institute, University of Sydney and Concord Hospital studied 1756 men aged 18 to 51 and found the combined jab was quicker and more effective than an androgen-only version. The World Health Organisation is understood to be planning an international study to test a three-monthly androgen-progestin combination injection for men.

The researchers complain that they have been hindered by a shortage of government interest and funding, and pharmaceutical companies have shown little interest in making it available to the public.

I’m all for any new method of birth control for men, and welcome this development. I’ll certainly be interested in reading the research when published, as previous versions of the male pill that were testosterone based caused mood swings and men to grow breasts (amongst other side effects). The researchers complain about lack of interest from pharmaceutical companies. I think the answer lies in the first comment posted on the article:-

“I think the lack of interest from government etc in furthering this drug is that they realise that men are too unreliable for it to work properly!! You see, if they forget, get too busy or whatever to go back to the doctor to have their next scheduled jab, well its not them that gets pregnant is it? Women DO remember (most anyway) to take their pill every day, and DO remember to go have their contraceptive injections when due, because they don’t want to get pregnant.”

Legislator wants changes to urinals in mens’ rooms

April 10, 2008 – 5:53 am

OK - not strictly related to men’s health, but this story caught my eye when going through my Google alerts.

In Baton Rouge, Louisiana a lawmaker wants the state to force contractors to construct barriers between urinals in men’s public bathrooms to require privacy partitions between urinals. The reason, according to the resolution is that “sexual offenders, sexually violent predators, and child predators can easily violate the privacy of others using urinals ….”I must admit that I didn’t think about certain types of people violating privacy, and I think in some ways naming the groups above is an excuse to implement this change. I know that going to the toilet in Roman times was a group activity, but it’s always struck me as rather odd that in this day and age men wouldn’t want privacy. So it’s a “Thumbs up” for me for this incentive!

www.wwltv.com

New studies published

March 20, 2008 – 9:52 am

I’ve been a bit lax lately about updating this topic - mainly because there seems to be a lot less newly published research this year than in previous years. Anyway, finally got round to looking up the new research, and I have three studies to report on.

The first one to report on was published in December 2007, and compared two local anesthetic techniques in men undergoing no-scalpel vasectomy. This study used 50 men, and gave them two different types of local anasthetic - one on each side. One side had the “No Needle” high pressure air jet, and the other side had the anasthetic administered by conventional needle. The air jet method of delivery had a significantly improved pain score for administration of the anasthetic agent, but the subsequent vasectomy was about the same pain and discomfort wise.

Study number 2 was published in January 2008, and looked at if differentsuture materials used for ligation of the vas deferens have any bearing on the success of the vasectomy. Oddly enough, in this study the answer was Yes, it does! In this study, patient records for 3005 consecutive vasectomies done in a district general hospital were reviewed and data analysed. A threefold increase in failure was noted when comparing Vicryl (absorbable, synthetic sutures) to traditional Chromic Catgut sutures.

Finally, a rare case history. It’s usual to note unusual case histories. In this instance, a 35-year-old healthy man developed a life-threatening saddle pulmonary embolism as a consequence of a deep vein thrombosis, resulting from limited mobilization shortly after an elective vasectomy. The author states that “This is the first report of a near fatal venous thromboembolic event resulting from vasectomy”. Should this be of concern? I’d suggest that due to the extreme rareity, no.

FDA approve home vasectomy test kit

March 4, 2008 – 7:18 pm

ContraVac, Inc., has announced that they have had approval from the U.S. Food and Drug Administration (FDA) to market SpermCheck Vasectomy® a simple diagnostic which confirms men’s post-vasectomy sterility. The device will enable men to test their post-vasectomy fertility status at home rather than requiring the patient to return to the physician’s office or a laboratory. The device will be commercially available in the U.S. as soon as Summer 2008. ContraVac will be presenting SpermCheck Vasectomy at the American Urological Association Annual Meeting in May 2008.

SpermCheck Vasectomy is an easy-to-use diagnostic device similar to a home pregnancy test for women. It is the first test with the sensitivity and specificity required to detect low numbers of sperm and the first at-home diagnostic to receive FDA approval for sperm testing after vasectomy. Physicians will be able to provide SpermCheck Vasectomy to their patients following their vasectomy or men can purchase SpermCheck Vasectomy directly from ContraVac.

Ed Leary, President of ContraVac said: “The convenience and privacy SpermCheck Vasectomy provides is anticipated to improve the compliance rate for post-vasectomy sperm testing, resulting in fewer unwanted pregnancies and providing greater peace of mind.” There are approximately 500,000 vasectomies performed each year and most physicians require two post-vasectomy sperm tests. The inconvenience and indignity associated with returning to the physician’s office or laboratory to supply semen samples has created an environment where nearly 35% of patients never return for their first sperm test and over 70% do not return for their second sperm test.

The study conducted on the product used 144 samples from 109 men according to the Contravac website.

Drop your pants and save a life

February 24, 2008 – 10:51 am

Not as odd as the title suggests. This story is from the UK, and just to clarify for US readers pants = underpants. Pants in the US = trousers in the UK to add a bit of further info :)

Anyway, this story is about an event planned to raise awareness of testicular cancer - especially in younger men. The event takes place at the Gloucester Rugby Club in Kingsholm, Gloucester and will be broadcast on the Channel 4 TV show “Embarrasing Illnesses”. The organisers expect more than 100 men will take part - including some of the club’s top players. The event, which will also raise money for several cancer charities, will be broadcast as part of an hour long Men’s Health special to be shown on Channel 4 in the spring, and it’s hoped that it will be the largest testicular self check ever undertaken in the UK.

Nearly 2,000 men are diagnosed with testicular cancer in the UK each year. Almost half of all testicular cancers occur in men under 35 years old, while only about 1 in 7 (14%) are diagnosed in men over 50 years. Testicular cancer kills 70 men in the UK every year, but if caught early enough, and that means checking yourself regularly, survival rates are 95%. Treatment for testicular cancer works very well and the vast majority of men are cured. Patients in Gloucestershire are more likely to survive testicular cancer and skin cancer than ovarian cancer or lung cancer, according to figures published last year by the South West Public Health Observatory. The five-year survival rate for patients suffering from testicular cancer was 91.24%.

Men who want to take part in the check should contact 020 7874 6666.

Man denied compensation after failed vasectomy

February 21, 2008 – 7:08 am

This story has been trundling on for a year or so, and this seems to be the final episode.

In New Zealand, a man has been denied compensation after an unsuccessful vasectomy because he was deemed to be “the author of his own misfortune”. He sought nearly NZ$102,000 in compensation from the doctor who botched his operation, after his wife became pregnant. But the Human Rights Review Tribunal has ruled the man should not get the money, despite the doctor being censured and fined over the failed operation because he did not follow medical advice after the procedure.

The Auckland doctor who performed the operation was found guilty of professional misconduct, censured and fined $1000 by the Health Practitioners Disciplinary Tribunal in 2006, and was also ordered not to do any more vasectomies for three years.

The review tribunal was told the couple, who have permanent name suppression, already had two children, but the wife’s pregnancies had been complicated, the New Zealand Herald reported. The husband told the tribunal that when he consulted Dr Wilson in July 2003, he was told that he should have his sperm count tested three months after the vasectomy and that he needed to be careful until testing showed that the procedure had been successful. The man said Dr Wilson did not tell him of the need to have a nil sperm count and did not arrange for him to have a test. He then suffered problems with bleeding, swelling and discomfort following the operation and the husband was taken to Auckland City Hospital. When he was discharged after three days, the husband said hospital staff told him the vasectomy had been carried out correctly so he was “unconcerned about requiring future sperm testing”.

In July 2004, his wife became pregnant and the couple sought an award of $101,950, including $4300 associated with the birth, $3000 for equipment such as a layette, $54,650 as a result of the wife’s lost income, $15,000 for lost autonomy and $25,000 for humiliation, loss of dignity and injured feelings.

However, the tribunal said the husband had “elected” not to have his sperm tested after the procedure.

http://www.tv3.co.nz

Drink and drugs can damage sperm, and affect future generations

February 21, 2008 – 7:07 am

Cynthia Daniels, of Rutgers University in New Jersey, (an expert in the relation between a father and child’s health) who led a seminar at the American Association for the Advancement of Science annual meeting in Boston, said: “Historically it has been assumed that exposures to the male will not affect his ability to pass defects on to children. If I was a young man I would not drink beer, I would not be smoking when I’m trying to conceive a child.”

“Men who drink excessive amounts of alcohol produce higher rates of sperm with abnormalities,” said Daniels. “There are many potential sources of harm to foetal health that remain unexamined. When 60% of birth defects are of unknown origin, why are we not examining one obvious potential source of harm?” Daniels’ advice to young couples trying for a baby is to think about both parents’ exposure to chemicals. “If you minimise your exposure to toxic substances then you might minimise your risks of reproductive harm.”

The good news for men is that sperm is produced continuously in a 74-day cycle, so the body does clean itself over time.

It is well known that a mother’s health is critically important in the resulting health of her baby, but there is now a growing body of evidence from both animal and human studies that paternal exposure to toxins can also adversely effect the development of a foetus, and that this can be passed down the generations. Scientists at the seminar listed problems including pregnancy loss, low birth weight, increased birth defects and childhood cancers in children fathered by men who were exposed to toxins, from pesticides and prescription drugs to wartime chemicals. Vietnam veterans exposed to agent orange, for example, have been shown to have children with increased rates of spina bifida.

In a study presented at the same seminar, Researcher Dr Matthew Anway described how his team exposed pregnant rats to the fungicide vinclozolin and found that the sperm of males had been affected. Anway explained the reason behind the changes as epigenetic, where chemicals in the environment can switch genes in the body on and off. Epigenetic changes are not usually passed to children unless they happen in germ cells such as sperm.

Dr Gladys Friedler, a Boston University scientist who has spent more than 40 years studying how a father’s health affects that of his children, said: “It takes two to tango. Males are as important as females in terms of their impact on the foetus and in later development.”

The pesticide research, presented at the conference, centred around vinclozolin, which is used on oilseed rape, grapes, fruit and vegetables. When it was injected into unborn rats in the first days of life, it caused prostate and kidney problems in the young animals. The creatures’ sons, grandsons and great-grandsons also suffered prostate and kidney defects, the University of Idaho study found. Previous work showed that exposure to vinclozolin in the womb can also affect the quality and quantity of sperm for several generations. It is thought that rather than mutating or changing the structure of the genes, the chemical causes subtle changes in how the genes work. Anway said the concentrations of the pesticide used were much higher than those people would normally be exposed to. But his experiments provided evidence that the effects of toxins can persist for generations.

Coffee is good for you!

February 21, 2008 – 7:02 am

Just been reading an article that looks at research into the effects of caffeine written for Men’s Health magazine. Interesting claims! The writers point out that on average, one study a day into the effects of caffeine is published, and they attempt to cut through the jumble to find some positives. But I think that reading between the lines, the old advive of “Everything in moderation” applies:-

“Caffeine is a complex compound. And it’s made even more so by America’s preferred delivery method, coffee. For instance, caffeine raises blood pressure, but habitual coffee drinkers are half as likely to die of heart failure as those who don’t fill their mug daily. And while caffeine spikes blood sugar, a java habit may help you dodge diabetes.

Your Brain: Soon after your first sip, caffeine begins to work its magic by causing the release of dopamine. Dopamine is a brain chemical that stimulates the area of your gray matter responsible for alertness, problem solving, and pleasure. You have that feeling of being activated, sharper, and on the ball, and you can also experience a mild mood-elevating effect. All of which goes a long way in explaining why there are around 9,000 Starbucks outlets in the United States, and more opening every day around the globe.

Be smarter instantly: Down a cup of joe just before your next meeting — it’ll boost your mind power for about 45 minutes, according to a recent Austrian study that directly measured the impact of 100 milligrams (mg) of caffeine on brain activity.

Be smarter for life: Refill your cup three times a day. Harvard researchers have determined that men who drink 4 cups of caffeinated coffee a day are half as likely to develop Parkinson’s disease as those who skip the java - presumably because caffeine keeps dopamine molecules active. What’s more, blocking adenosine may slow the buildup of amyloid-beta, a toxic brain plaque that’s associated with Alzheimer’s disease.

Your Heart: Adenosine helps blood vessels relax. But once caffeine infiltrates the receptors that line vessel walls, your arteries constrict, causing your blood pressure to rise. In fact, research has shown that blood pressure may increase by as much as 10 points in nonhabitual drinkers. Yet when Harvard researchers tracked the coffee intake of more than 128,000 people, they determined that drinking more than six cups of coffee a day didn’t boost the chance of developing heart disease. And last year, scientists at Brooklyn College found that men who drank 4 cups of caffeinated coffee daily had a 53 percent lower risk of dying of heart disease than those who never took a sip. “If you don’t have hypertension to begin with, the temporary blood-pressure increase from a cup of coffee isn’t a problem,” says Matthew Sorrentino, M.D., a cardiologist and professor of medicine at the University of Chicago. “Plus, the impact on blood pressure tends to be smaller in habitual caffeine drinkers because their bodies become somewhat tolerant to its effects.”

Take your health history into account: If caffeine makes your heart race or skip beats, you’re probably genetically sensitive to the stimulant. “Although this may sound serious, symptoms such as palpitations are actually considered innocuous, unless you’ve had a recent heart attack,” says John Kassotis, M.D., a cardiac electrophysiologist at SUNY Downstate, in Brooklyn. Still, Dr. Kassotis suggests playing it safe. His rule of thumb: If you think you’re caffeine-sensitive, consult your physician to determine if you should limit your intake.

Stick with antioxidant-rich java: Scientists aren’t sure whether it’s the caffeine or the antioxidants in coffee or a combination of the two that provide the aforementioned cardiovascular benefits. But unless you’re caffeine-sensitive, go with the leaded variety. Research shows that antioxidant levels are decreased by about 15 percent in decaf.

Your Muscle: Because caffeine revs up your central nervous system, it slightly increases your heart rate and breathing rate, both of which help prepare your body for peak performance. Caffeine may also have a direct effect on your muscles. Here’s how: Calcium must be released within a muscle fiber in order for that fiber to contract, and caffeine may block the adenosine receptors attached to muscle fibers, triggering electrical activity that prompts bigger bursts of calcium. “The result is a stronger muscle contraction,” says Terry Graham, Ph.D., a professor of human health and nutritional sciences at the University of Guelph, in Ontario.

Jumpstart your workout: Studies show that consuming 140 to 400 mg of caffeine 30 to 60 minutes prior to exercise can improve both speed and endurance and make your workout seem easier. But to achieve those effects, researchers have used either caffeine pills or caffeinated soda. The reason: “Many other chemical compounds in coffee appear to counteract caffeine’s ability to impact your exercise session,” Graham says. Now you know why energy drinks were created. Looking for a boost? Try Celsius, which is sugar-free and contains about 200 mg of caffeine per 12-ounce can. To determine if it’s enhancing your performance, be sure to monitor how it impacts your exercise session both mentally (”My workout seemed easier” or “I felt like I was dragging”) and physically (”I completed more repetitions” or “I didn’t improve”).

Use caution: If you have heart problems or a family history of heart disease, avoid high-caffeine energy drinks for 4 hours before exercising. A 2006 study in the Journal of the American College of Cardiology determined that 200 mg of caffeine decreases bloodflow to the heart by up to 39 percent during exercise because it constricts coronary arteries.

Your Liver: When your central nervous system is activated, so is your body’s fight-or-flight response. This causes the release of stress hormones such as cortisol and adrenaline. These in turn signal your liver to pump sugar into your bloodstream. After all, had you been in a truly stressful situation — say, face-to-face with a cranky barista–your body would need that sugar for quick energy. But in everyday life (read: sitting at your desk), extra blood sugar is the last thing you need, because it signals your body to store fat and increases your risk of diabetes.

Keep your blood sugar in check: Forgo the sugar in your coffee and you’ll actually reduce your risk of developing diabetes, according to multiple studies. For example, in 2005, Harvard University researchers determined that drinking 5 cups of coffee a day cuts in half the risk of developing diabetes. Scientists aren’t sure why coffee may have a protective effect against diabetes, but credit its high level of disease-fighting antioxidants. While visiting Starbucks, we recommend a Caffè Americano, which is coffee at its finest: strong and flavorful, but sugar-free.

http://www.menshealth.com/

New vasectomy reversability implant

February 18, 2008 – 6:50 am

The China Daily said on Thursday February 14, that Chinese doctors have developed a new technique in birth control surgery for men that could be made available to the public next year. The new Chinese method involves making a small incision along the testicle into which doctors place a tiny tube. The director of Guangzhou Family Planning Technology Center informed that the tube functions as a filter that blocks sperm and this vasectomy is reversible by simply taking out the tube.

I don’t have a source for this as yet - it was spotted on another blog.

If you live in Wiltshire, UK your chances of getting an NHS vasectomy have just increased

February 16, 2008 – 7:30 am

Wiltshire, UK.

I noticed a news alert that Wiltshire Primary Care Trust is set to reverse its policy on not providing sterilisation and vasectomies. According to the report, The PCT decided soon after it was formed in October 2006 not to fund both procedures to save money. Before that date sterilisation procedures were available free of charge. Now it’s news to me that any area in the UK had a ban on providing sterilisation procedures. I do know some areas farm vasectomy out to other providors such as Marie Stopes, but it was my impression that it wa national policy to fund vasectomy and female sterilisation.

What’s angered people about this policy is the inconsistency it was applied with. They have complained that the cost of providing them with other forms of contraceptives or the cost of increased numbers of abortions is actually more expensive. They have also complained that other local PCTs do routinely commission these procedures. They currently are only considered as exceptions and request for treatment are dealt with through the Exceptions Committee. So one day, your chances of getting a vasectomy are good, because the committee thinks it’s a good idea, but have the case heard next day and your out of luck buddy!

Daft decision to implement this policy - sane that they are reversing it.